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Lipofuze has 6 patented ingredients
Created by Integrity Nutraceuticals, Thermodiamine is a patented and processed form of evodiamine, a quinozole alkaloid isolated from the unripe fruit of evodia rutaecarpa. It consists of evodine, evodiamine, dehydroevodiamine, and rutaecarpiine in one. It works to support and increased level of lipolytic or fat burning activity. Similar to the cayenne pepper, it appears to have a positive effect on the vanilloids receptors. These regulate natural body temperature and therefore thermogenic fat burning. But it does not come with the common side effects of capsaicin such as burning or indigestion, nor does it cause overstimulation, insomnia, etc, like its stimulant based counterparts. Instead, it works to increase the output of catecholamines like epinephrine and norepinephrine, simultaneously increasing peripheral heat loss and caloric expenditure.
In a recent study, Kobayashi Y et al 2001, Thermodiamine was tested in combination with a high fat diet for 21 days. Room temperature was maintained with patients, and subjects were allowed free access to food and water at their will. The Thermodiamine diet contained 0.03% evodiamine with a 30% fat diet. They found that during that study, the perirenal fat weight and epididymal fat weight were significantly reduced, not only leading to a loss of the obvious body fat, but an improvement in the health of the heart and other major internal organs.
A product of Integrity Nutraceuticals, Razberi-k is also known as 4-(4-hnydroxyphenyl)butan-2-one. This ketone is unique to the raspberry fruit, and it is among the bioactive components of raspberries thought to promote better health benefits. According to scientists, it works to support body fat reduction in 2 ways. First, it decreases the natural body absorption of dietary fat. Secondly, it works to reduce the absorption of dietary fat, inhibiting trioleolglycerol hydrolysis. This may increase the translocation of hHSL in fat cells and increase brown adipose tissue, therefore helping you to increase thermogenesis and oxidation of body fat. But how does this apply to you?
A study conducted on Razberi-K showed that subjects experienced significant reductions in weight and body fat, even when the razberi-k supplement was combined with a high fat diet. When taken in doses of 100mg twice daily, in some it significantly reduced weight gain associated with a high fat diet, and in others it went so far as to promote greater weight loss results. Further studies have continued to demonstrate that when supplemented even into a high fat diet, razberi-k continues to show significant reductions in fat as compared to the placebo.
A common form of wakame seaweed, FucoPure is standardized to 10% fucoxanthin. It is an accessory pigment in the chloroplasts of brown algae, and it absorbs light primarily in the blue green to yellow green area of the color spectrum. Studies have been conducted primarily at Hokkaido University that demonstrate that Fucoxanthin and FucoPure can help you to promote greater fat burning in the fat cells and white adipose tissue.
The most recent study conducted on FucoPure administered a specialized formulation to subjects, refining it to make sure to get the most potent form of fucoxanthin available. Diet was kept the same, both groups consuming a high fat diet. Thermogenic effects significantly increased, and a rise in UCP1, UCP2, and UCP3 proteins was noted. Because of the effect on UCP2, which has been connected to incidence of type 2 diabetes and heart disease, it has also been suggested that FucoPure can simultaneously improve the healthy functions of the body that can sometimes be negatively affected by obesity.
Described as a patented phytonutrient for weight management, Forslean works by specifically increasing natural production of lean muscle mass, therefore increasing your metabolism while also defining the body mass. It is manufactured through a proprietary process and works as a standardized extract of the coleus forskohlii plant. It is the only coleus forskohlii supported by US patent as a forsoklin composition that supports the building of lean muscle mass.
Multiple studies have indicated that Forslean can have a positive impact on the lean body mass. Recently, forslean was tested in the open field study with 6 overweight women with a BMI greater than 25. Each was given 250mg of forslean in hard shell capsules. This was dispensed twice daily for 8 weeks, and subjects were instructed to take one capsule in the morning and one in the evening, an hour before each major meal. Each was asked to maintain previously set daily activity levels and eating habits, and all factors were monitored by questionnaire. In this 8 week trial, mean body weight and fat content significantly decreased, and lean body mass significantly increased compared to baseline values. Lower blood pressure levels were also observed with use of this product.
A product of Creative Compounds, GuggulEZ100 guarantees users a 95% concentration of E&Z guggulsterones proven to promote substantially greater weight loss results. Found in traditional Ayurvedic medicine, guggulsterones have been shown to maintain normal blood lipid levels, improve skin texture, optimize thyroid activity with more iodine, and increase the metabolic rate with natural hormones.
Studies on GuggulEZ100 used 12 patients, 6 in each group. Guggulsterones showed a marked reduction in cholesterol levels in the liver. It reduced bile acids, and subjects were found to be considerably healthier. Skin tone took on a healthier glow, and weight loss significantly increased with a higher metabolism and increased lean body mass.
A major extract of the black pepper extract, Bioperine has two major values. First, it works to enhance the transportation of nutrients into the blood. It helps you to absorb other valid ingredients far more quickly and efficiently, making them naturally more potent and effective. In addition to that, due to its spicy taste, much like capsaicin, it can help you to increase natural thermogenic lipolytic activity.
In studies, Bioperine, much like capsaicin, has been specifically used to target the vanilloid hormones. Studies used 12 healthy adult male subjects between the ages of 20 and 47. Each was given a formulation that also included coenzyme Q10. Following a single dose of 90mg of coenzyme Q10 and 5mg bioperine, it was shown that bioperine significantly enhanced the gastrointestinal absorption of other nutrients.
Lipofuze Has 4 Additional Clinically Tested Ingredients
Green Tea: Green tea has been used in most major Asian countries as a regular part of everyday living for over 5000 years. It has also been used in many aspects of traditional medicine. Some consume an average of a liter per day, aiding in everything from digestion to circulatory and heart health. Recently, it has spread to Western cultures.
In the past few decades, study of green tea has significantly increased, and literally hundreds of clinical studies have been conducted on all of its health and weight loss related benefits. It has been long purported that green tea may be largely responsible for the lower body weight and superior health standards of many Asian countries.
Since the scientific community took note of green tea, multiple studies have suggested that it rolls health and weight loss benefits into one. Rich in catechins and natural antioxidants, green tea works to eliminate harmful free radicals while also clearing the arteries and reducing the risk of heart disease, dental cavities, kidney stones, and cancer. It has also been shown to improve bone density and cognitive function.
Weight loss studies have shown marked reductions in body fat and increases in thermogenic fat burning. A study performed at Birmingham UK University demonstrated that the average fat oxidation of test subjects was 17% higher than their placebo counterparts. Likewise, a study performed at the Queen Margaret University in Edinburgh showed that when subjects between the ages of 19 and 37 consumed 4 cups of green tea a day for 14 days, marked reductions in blood pressure, fasting total cholesterol, body fat, and body weight were noted. Further studies have consistently shown marked reductions in body fat, body weight, cholesterol lipid levels, and many other obesity related areas.
Capsaicin: The stick by which many stimulant free fat burners are measured, Capsaicin was the first ingredient noted to specifically target the vanilloids hormones in the body. It has been found in the cayenne pepper and linked to numerous health benefits and weight loss benefits. With its spicy taste, it has been said to improve natural thermogenic and lipolytic fat burning, and because of its antioxidant content, it has also been said to significantly improve health benefits.
Capsaicin is the most potent component of the cayenne pepper, and its pungent taste and body has been shown to significantly reduce body fat. When combined with a high fat diet, those who were not using capsaicin gained twice as much as those who did. Some also suggest that it enhanced the lipid absorption throughout the body, and energy use was far more significant in the test group than the placebo group.
Other studies have suggested that capsaicin has many other benefits, some connected to obesity and others not. It obviously produces a short period of extra heat in the body, burning more fat. But it has also been explored for treatment of type 1 diabetes by researchers in Toronto, Canada. And some studies in Japan have suggested that it may inhibit the growth of precancerous cells. Finally, it has been used to naturally reduce the inflammation associated with rheumatoid pain.
Synephrine: Functioning under many names such as citrus aurantium, bitter orange extract, and zhi shi, synephrine is the chemical cousin to the previously popular ephedrine extract. Ephedrine, before its ban, was known as the most powerful weight loss supplement to be legal on US markets. But after demonstrating side effects such as heart attack, stroke, and death, it was removed. Synephrine has been used to replace the effectiveness of its chemical cousin without causing the same side effects.
Synephrine significantly increase lipolytic and thermogenic activity. It increases energy and the use of calories found in food consumed. Synephrine has been used to suppress appetite and increase natural metabolism, while also being rich in tyramine and octopamine, which have been used to significantly increase metabolism, and reduce the body’s absorption of fat cells.
When tested in a number of different studies, synephrine has demonstrated marked increases in fat burning, metabolism, energy, and reductions in appetite. It has shown weight loss benefits similar to those of ephedrine. But no major side effects have been noted as of yet. Most recognize 250mg to be the optimal dose for the best weight loss results with both ephedrine and now synephrine.
DHEA: A stimulant free and potent thermogenic fat burner, DHEA is an endogenous natural hormone produced in the adrenal glands, gonads, and the brain. It has been studied in connection with depression, memory, physical performance, cardiovascular health, cancer, diabetes, and more. But it has been best known for its fat burning abilities.
DHEA has been specifically used to improve thermogenic activity and healthy thyroid function in the body. It regulates the body’s natural heat production and metabolism, and improves the thyroid function of the body. Studies have demonstrated that those consuming DHEA lost a significant amount more weight as opposed to those who did not, and it showed a significant reduction specifically in body fat with elevated T3(thyroid) hormone levels.
Successful studies show one of the lowest requirements of any diet supplement. While other supplements require 1000mg or more, DHEA only requires 200mg doses twice daily to demonstrate successful and significant reductions in body fat and body weight.